Probiotic Microorganism

The term “probiotic” remains undefined legally in many countries, and regulatory approaches differ among countries worldwide. Diverse categories encompass probiotic products, including: food, functional food, novel food, natural remedy (Denmark Sweden and Finland), natural health product (Canada), dietetic food (Italy), dietary supplement (USA), biotherapeutic and pharmaceuticals (probiotic pharmaceuticals are available in Canada, China, eastern European countries, France, Germany, Belgium, Austria and Italy). There is no official definition of probiotic in Japanese regulation, but several probiotic and prebiotic products have achieved FOSHU (foods for specialized health use) status, with health statements being approved by the Japanese Ministry of HealthWhile few studies have established the minimum effective dose of a probiotic to convey a physiological effect, probiotic-induced changes are rarely seen at daily doses of less than 10 8colony forming units (cfu). However, one can only speculate as to how many probiotic cells reach target sites alive. Probiotic bacteria that are tolerant to acid stress would be expected to survive well during stomach passage. Genomic regions, identified through genome sequencing, that may help identify regions critical to the survival and functionality of commensal or probiotic organisms in their corresponding habitats might include: conserved versus distinct gene sets , genes resulting from recent horizontal transfer, altered GC content–islands/regions of adaptability
 

  • Enteric microbial community profiling
  • Functional Genomics
  • Metabolomics of Probiotics
  • Genetic modification: Recombinant probiotics
  • Probiotics-Pathogen Competition

Probiotic Microorganism Conference Speakers

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